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Done Deal: LEO Pharma Finalizes Acquisition of Key Assets From Timber Pharmaceuticals 

The Dermatology Digest

LEO Pharma now owns TMB-001 as well as certain other assets from Timber Pharmaceuticals following its chapter 11 bankruptcy filing. All employees of Timber Pharmaceuticals will transition to LEO Pharma’s offices in New Jersey, US, the Company reports. The TMB-001 project continues as planned and without changes within LEO Pharma.

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Ligand Pharmaceuticals Launches Pelthos to Accelerate Commercialization of Zelsuvmi for Molluscum; Appoints New CEO

The Dermatology Digest

Ligand Pharmaceuticals is launching Pelthos Therapeutics (Pelthos), a biopharmaceutical company, and has appointed Scott Plesha as Chief Executive Officer to accelerate the commercialization of berdazimer topical gel, 10.3% (Zelsuvmi) for the treatment of molluscum contagiosum. Watch Now: Nanette B. in September 2023.

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Distinct Pattern in Protein Production May Predict Severe Side Effects From Melanoma Treatment

The Dermatology Digest

Moreover, the researchers found that this heightened gene signature, as evidenced by the production of spleen tyrosine kinases, or the SYK pathway, did not interfere with the effectiveness of therapies in preventing recurrence of melanoma. The impact was connected only to side effects.

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LEVEL UP Period 2 Data: AD Patients Who Switched From Dupilumab to Upadacitinib Hit Higher Treatment Targets

The Dermatology Digest

Atopic dermatitis (AD) patients who switched to upadacitinib (Rinvoq, AbbVie) from dupilumab (Dupixent, Regeneron, and Sanofi) hit higher treatment targets, according to results from Period 2 of the LEVEL UP study. Both groups had similar proportions of patients with treatment-emergent adverse events (TEAEs).

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Sneak Peek Inside the CSU Treatment Pipeline

The Dermatology Digest

Jonathan Silverberg, MD, PhD, MPH, Professor of Dermatology at The George Washington University School of Medicine and Health Sciences in Washington, DC, discusses the need for a comprehensive treatment approach for CHE.

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Warts and All: Verrica and Torii Team Up to Fund Global Phase 3 Trial of YCANTH for Common Warts

The Dermatology Digest

Verrica Pharmaceuticals Inc. has entered into an amendment to its existing licensing agreement with Torii Pharmaceutical Co. Torii) to jointly conduct a global pivotal Phase 3 clinical trial of YCANTH (cantharidin) for the treatment of common warts. With a prevalence of approximately 22 million patients in the U.S.

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Is a Pharmacologic Treatment for Neurofibromatosis Type 1 Skin Tumors on the Horizon?

The Dermatology Digest

Current treatment for neurofibromatosis type 1 skin tumors involves monitoring the tumors and removing them surgically if necessary, but this isn’t ideal as neurofibromas can grow back and continue originating in other parts of the body, plus surgery leaves scars. The key takeaway from these experiments is the lasting impact of the treatment.