The Dermatology Digest

JANUARY 5, 2024

The last patient has been dosed in Part 2 of Verrica Pharmaceuticals Inc.’s The Phase 2 trial is a 2-part, open-label, multicenter, dose-escalation, proof-of-concept study with a safety run-in designed to assess the safety, pharmacokinetics, and efficacy of VP-315 in adults with biopsy-proven basal cell carcinoma.

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The Dermatology Digest

NOVEMBER 30, 2024

LP-310, developed by Lipella Pharmaceuticals for the treatment of oral lichen planus (OLP), is currently in Phase 2 clinical trials. Lipella has received an Investigational New Drug (IND) approval for a Phase 2a multicenter dose-escalation trial evaluating the safety and efficacy of LP-10 in subjects with symptomatic OLP.

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The Dermatology Digest

JANUARY 16, 2024

Food and Drug Administration (FDA) has updated the label for dupilumab (Dupixent, Regeneron Pharmaceuticals, Inc. and Sanofi), adding efficacy and safety data for people aged 12 years and older with atopic dermatitis (AD) and uncontrolled moderate-to-severe hand and/or foot involvement. and Sanofi report. “We

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The Eco Well Blog

OCTOBER 18, 2021

Outside of cosmetics, they are used extensively in other products - from plastic to flooring, pharmaceuticals to food packaging. The only phthalate still in use worldwide is diethyl phthalate, which can be used without restriction because of its good safety profile. DMP and DBP have largely been phased out since 2007.

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The Dermatology Digest

JANUARY 8, 2025

Key results of the study showed: Safety: ET-02 was found to be safe and well tolerated. Eirion plans to begin a Phase 2 clinical trial (N150) in 2025 with a 6-month treatment period with the goal of confirming ET-02’s safety and efficacy. A final assessment of the subjects was made one week after the treatments ended.

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The Dermatology Digest

JANUARY 4, 2024

The clinical results demonstrated that DMB-3115 and its reference product, ustekinumab, are highly similar, and have no clinically meaningful differences in terms of quality, safety and efficacy. As a global subsidiary of Intas Pharmaceuticals, Accord BioPharma will be responsible for U.S. commercialization.

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The Dermatology Digest

FEBRUARY 27, 2024

where biologics represent well over 40% of all pharmaceutical spending. We strongly believe that biosimilars are important in addressing inflationary pressures in the healthcare system across all markets, especially in the U.S.

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The Dermatology Digest

JULY 22, 2024

Launching Uzpruvo at the earliest opportunity in Europe’s largest pharmaceutical markets, promotes access by creating competition,” says STADA CEO Peter Goldschmidt in a news release. Launches in further European countries are scheduled over the coming months, following national price approvals, via a fully European supply chain.

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The Dermatology Digest

APRIL 22, 2024

Treatment was well-tolerated and no new safety signals were identified. Notably, in patients that previously had an inadequate response to dupilumab, two-thirds achieved EASI-90 and vIGA 0 or 1 when treated with eblasakimab,” says Dr Carl Firth, Chief Executive Officer of Aslan Pharmaceuticals, in a news release.

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Aesthetics Advisor

AUGUST 15, 2023

Since fenbendazole is a veterinary medicine, and is not licensed for human use and there is no specific human safety data available. The similar human forms of this class of medications, mebendazole and albendazole, have been used for parasitic infections for many years and have a good safety record. chemotherapy?

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The Dermatology Digest

AUGUST 14, 2024

Verrica Pharmaceuticals Inc.’s The Phase 2 trial is a 2-part, open-label, multicenter, dose-escalation, proof-of-concept study with a safety run-in designed to assess the safety and tolerability, pharmacokinetics, and efficacy of VP-315 when administered intratumorally to adults with biopsy-proven basal cell carcinoma.

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The Dermatology Digest

OCTOBER 26, 2024

Learn more about LEVEL UP, the first head-to-head trial in AD assessing upadacitinib (Rinvoq, AbbVie) at a starting dose of 15mg daily vs. dupilumab (Dupixent, Sanofi and Regeneron Pharmaceuticals) at its labeled dose, in Raising the Bar in Atopic Dermatitis (AD): Unpacking the practice-changing implications of the LEVEL-Up study in AD.

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The Dermatology Digest

FEBRUARY 26, 2024

The EPI-U01 study was a randomized, placebo-controlled, cross-over study evaluating the safety and efficacy of epinephrine nasal spray in patients with chronic spontaneous urticaria (CSU) treated with chronic medications who were still experiencing flares.

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AAAMS

MARCH 26, 2024

Licensed medical professionals can only purchase this controlled substance through pharmaceutical supply chains. Although nonmedical staff can be instrumental in patient care, providers should never allow aestheticians to perform Botox or dermal filler, as it could risk the patient’s safety and the provider’s license and legal standing.

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AAAMS

MARCH 26, 2024

Licensed medical professionals can only purchase this controlled substance through pharmaceutical supply chains. It blocks nerve signals in the muscles at the injection site, causing temporary paralysis. Botox supports many indications and off-label uses with low risks of serious side effects.

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The Beauty Brains

APRIL 1, 2019

So, pharmaceutical companies are spending money researching this. J&J might discover something as they are a pharmaceutical company, but most beauty companies are not set up to develop these types of products. As far as safety goes, yes it’s mostly safe to do at home. And a product like this would be a drug.

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The Dermatology Digest

MARCH 6, 2024

Benzoyl Peroxide-based acne medications can become unstable and form benzene, a known human carcinogen, according to new research from Valisure, an independent laboratory focused on testing the purity and safety of pharmaceutical drugs and consumer products. Food and Drug Administration (FDA).

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Aesthetics Advisor

DECEMBER 6, 2023

I suspect the biggest issue is easy access to melatonin and its ill-perceived safety,” sleep medicine pediatrician Dr. Muhammad A. Doctors still do not know why melatonin supplementation may be associated with death, given its assumed high safety profile. Dr. Perry recommends pharmaceutical-grade melatonin for short-term use.

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Kind of Stephen

APRIL 7, 2022

What stands out to me about the Atralin Gel is the butylated hydroxytoluene (BHT), an antioxidant commonly used in pharmaceuticals and food. The second formula didn’t use encapsulation, but also had minimal-to-no degradation of the tretinoin. Only the Atralin Gel formula was tested. on KindofStephen.

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The Beauty Brains

JULY 3, 2016

Apparently this is well studied because I found a paper titled “ Effect of Film Irregularities on Sunscreen Efficacy ” in the Journal of Pharmaceutical Science. Skin safety Of course the biggest concern is one of safety. There are multiple regulations which control what may and may not be used in cosmetics.

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Aesthetics Advisor

FEBRUARY 28, 2024

2 However, as "modern" medicine and the pharmaceutical industry ramped up the health care machine, vitamin C quickly fell out of favor as it is inexpensive, easy to administer and has very few side effects. In other words, as effective as vitamin C is in prevention and treatment, you can’t make money prescribing or manufacturing it.

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Aesthetics Advisor

JUNE 3, 2024

Both drugs come from the Danish pharmaceutical company Novo Nordisk, whose market capitalization has soared to $609 billion, surpassing Tesla’s valuation by $40 billion. 2023;330(18):1795-1797 22 Expert Opinion on Drug Safety, 22(6), 455–461 23 Int J Clin Pharm. Glucagon-Like Peptide-1 Receptor Agonists (Archived) 11, 12 Mol Metab.

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Aesthetics Advisor

JULY 23, 2024

Important safety note: Resveratrol is not suitable for people undergoing blood-thinning medication. doctors from the pharmaceutical giant GlaxoSmithKline. Rhonda Patrick had with Harvard Professor of Genetics Dr. David Sinclair, the latter recommends the storing of resveratrol in a cold dark environment at all times.

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First Derm

DECEMBER 26, 2023

Evaluation of safety and efficacy of ketoconazole 2% and zinc pyrithione 1% shampoo in patients with moderate to severe dandruff–a postmarketing study. Asian Journal of Research in Pharmaceutical Science. Association of Malassezia species with dandruff. The Indian journal of medical research. 2014;139(3):431-437. 2017;98(12).

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Aesthetics Advisor

AUGUST 6, 2023

Drugs that Prevent Colorectal Cancer Several pharmaceutical agents are showing signs of effectiveness in preventing colorectal cancers. Prospective double-blind randomized study on the efficacy and safety of an n-3 fatty acid enriched intravenous fat emulsion in postsurgical gastric and colorectal cancer patients. 2014;6(10):4043-57.

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Aesthetics Advisor

AUGUST 7, 2023

However, it can interfere with some medications, including oral chemotherapy, high blood pressure medications, blood thinners, cholesterol medications, immunosuppressive drugs, and pharmaceutical diabetes treatments ( US News ). Women who are pregnant or breastfeeding should avoid berberine. Recommended dosages can vary between brands.

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Aesthetics Advisor

JANUARY 3, 2024

However, it can interfere with some medications, including oral chemotherapy, high blood pressure medications, blood thinners, cholesterol medications, immunosuppressive drugs, and pharmaceutical diabetes treatments. It has an excellent safety profile and can be taken with any other supplements, including glutathione."

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Aesthetics Advisor

DECEMBER 3, 2023

The Timing of Your Supplements Matters When and how you take supplements — such as with or without food and in the morning or evening — can make a difference in their safety and effectiveness. For more details about methylene blue be sure to view my interview with the leading researcher in the field, Francisco Lima-Gonzalez, Ph.D.

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The Dermatology Digest

OCTOBER 10, 2024

Groen and Zaaijer propose utilizing a new workflow involving human 3D-skin models with varying pigmentation levels that could offer pharmaceutical companies an efficient method to assess drug binding properties across different skin types. Skin pigmentation should be considered as a factor in safety and dosing estimates,” Zaaijer says. “We

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The Beauty Brains

MARCH 4, 2019

They also have advice from a body called the scientific committee for cosmetic safety or SCCS, which is composed largely of academics with an interest in medicine and general science. This is an idea that has been adopted from the pharmaceutical industry where it has been going on for a long time. Smaller producers? Not so much.

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Aesthetics Advisor

NOVEMBER 16, 2023

A meta-analysis of randomized controlled trials, published in Pharmaceuticals (Jan 2023), is titled “Protective Effect of Vitamin D Supplementation on COVID-19-Related Intensive Care Hospitalisation and Mortality: Definitive Evidence from Meta-Analysis and Trial Sequential Analysis”. According to a review ( Cardinali et al.

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The Dermatology Digest

FEBRUARY 5, 2024

Verrica Pharmaceuticals Files Lawsuit Against Canadian Drug Manufacturer for False Advertising, Unfair Competition Verrica Pharmaceuticals Inc. Verrica Pharmaceuticals Files Lawsuit Against Canadian Drug Manufacturer for False Advertising, Unfair Competition Verrica Pharmaceuticals Inc.

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Aesthetics Advisor

JANUARY 18, 2024

Currently there are three main categories of pharmaceutical agents used to treat or prevent ischemia issues: thrombolytics, antiplatelets, and anticoagulants. Is there not a safer and also effective natural option for helping patients besides the above categories of pharmaceuticals? In a paper published in 2007, Zhao et al.

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Aesthetics Advisor

SEPTEMBER 15, 2023

The pharmacology, toxicity, and safety data for NO use in humans has been well-established for decades. Moreover, Glenmark Pharmaceuticals received manufacturing and marketing approval for the Nitric Oxide Nasal Spray (NONS) as part of an accelerated approval process. You can purchase it online on Amazon.com.

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US Dermatologt Partners

JANUARY 7, 2025

And some of the reviews authors were consultants for a skin care pharmaceutical company, presenting a conflict of interest. Because of these potential safety concerns and the lack of evidence of benefit, Dr. Watchmaker and the other dermatologists recommended not using estrogen as skin care until more research is done.

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Aesthetics Advisor

AUGUST 16, 2023

Robert Kushner of Northwestern University, who serves on Novo Nordisk’s advisory board, told NPR, “This hormone is telling your brain, I'm full, I don't need to eat anymore … What the pharmaceutical companies have done is taken this hormone that is naturally occurring and restructured it into a drug.” 2023 Mar 28. doi: 10.1016/j.cell.2020.04.043.

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First Derm

NOVEMBER 25, 2023

Relationship impact : honesty and safety measures are key. 20] The American College of Obstetricians and Gynecologists (ACOG) emphasizes the significant morbidity and mortality caused by HPV and strongly recommends HPV vaccination to eligible patients, stressing the benefits and safety of the vaccine. Current pharmaceutical design.

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