Fri.Apr 18, 2025

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Pinworm Medication Shows Promise in Treating Merkel Cell Carcinoma

The Dermatology Digest

A common pinworm medication may stop and reverse cancer growth in Merkel cell carcinoma, according to research out of the University of Arizona Cancer Center in Tucson, AZ. Pyrvinium pamoate, a medication approved by the Food and Drug Administration in 1955 to treat pinworms, has been shown to have antitumor potential in several different cancers, including breast, colorectal, pancreatic, and bladder cancers.

Medical 75
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Gratitude and Saying Thanks

Skin Inc

Saying thanks can positively impact client retention. Gratitude makes the relationship more personal and builds customer loyalty. Saying thanks also encourages word-of-mouth marketing.

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FDA Approves First Targeted Therapy for CSU in More Than a Decade

The Dermatology Digest

Jason Hawkes, MD, MS, a Dermatologist and Investigator atOregon Medical Research Center in Portland, OR,discusses the significance and implications of the U.S. Food and Drug Administrations approval of dupilumab (Dupixent, Sanofi & Regeneron) for patients aged 12+ years with uncontrolled Chronic Spontaneous Urticaria (CSU) who remain symptomatic despite use of H1-antihistamines.It’s a win in dermatology because these are patients that we can easily recognize and diagnose and now we hav

Therapy 54
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FDA Approves Dupilumab for Adolescents and Adults With H1 Antihistamine-Refractory Chronic Spontaneous Urticaria

Dermatology Times

Dupilumab becomes the first targeted therapy approved for chronic spontaneous urticaria in more than a decade.

Therapy 73
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Hair Escape Retreat Has Successful Debut in Costa Rica

Beauty Launchpad

Hair Escape, an exclusive retreat designed to provide a space for hairstylists to recharge, learn and connect, held its debut event at Gracias Madre in Jaco, Costa Rica.

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Treating Rosacea and Other Concerns with Generative Skin’s Ingredient Library

Dermatology Times

As a patient with rosacea herself, Anastasia Georgievskaya highlights the innovation of Generative Skin in patient education.

Rosacea 46

More Trending

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Retirement Plans 101: What Dermatologists Need to Know

Dermatology Times

QRPs are key to dermatologists' retirement planslearn the benefits, drawbacks, and how to choose the best strategy for your financial goals.

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Immunocompromised Patients with Actinic Keratosis Respond Well to LED Daylight Photodynamic Combination Therapy

Dermatology Times

Solid organ transplant recipients saw a 79.6% decrease in lesions 12 weeks after the treatment sessions.

Therapy 41
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The Hidden Complexity of Reporting AEs

Dermatology Times

Trials often exclude high-risk patients, limiting the real-world relevance of their safety findings.

Safety 41
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Art Meets Medicine in Bold New AAD Showcase

Dermatology Times

Spearheaded by John Zampella, MD, FAAD,and Mitchell Hanson, the project highlights how art can foster community and empathy in dermatology.

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Daily Derm Times: April 18, 2025

Dermatology Times

Catch up on dermatology news, highlights, and insights from the past 24 hours.

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Things to Consider With Treatment Sequencing for Pediatric Atopic Dermatitis

Dermatology Times

James Song, MD, FAAD, discusses how the treatment of pediatric atopic dermatitis (AD) demands personalized consideration of disease severity, patient age, affected areas, and treatment history. Ruxolitinib cream may address gaps by providing a nonsteroidal alternative with fewer adverse effects, potentially delaying or reducing systemic therapy needs.

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Utility of Head-to-Head Studies in Atopic Dermatitis and Future Research Directions

Dermatology Times

Panelists discuss how data from head-to-head clinical trials comparing different therapeutic options in atopic dermatitis inform treatment decisions while exploring critical gaps in research that future studies need to address.

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Identifying and Addressing Critical Gaps in Pediatric Atopic Dermatitis Treatment with Ruxolitinib Cream

Dermatology Times

James Song, MD, FAAD, discusses how ruxolitinib cream addresses a significant treatment gap in pediatric atopic dermatitis by providing a non-steroidal topical option with efficacy comparable to medium-potency corticosteroids but without the associated safety concerns.

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Benefits of Nonsteroidal Topical JAK Inhibitors for Moderate Pediatric Atopic Dermatitis

Dermatology Times

James Song, MD, FAAD, discusses how topical Janus kinase inhibitors offer distinct advantages for children with moderate atopic dermatitis by providing effective inflammation control without the adverse effects of topical corticosteroids, particularly in sensitive areas like the face and intertriginous regions.

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Future Perspectives: Can Innovative Topical Therapies Like Ruxolitinib Reduce Systemic Treatment Dependency in Pediatric AD?

Dermatology Times

James Song, MD, FAAD, discusses how emerging topical JAK inhibitors like ruxolitinib cream may reduce the necessity for systemic therapies in select pediatric atopic dermatitis patients by effectively controlling moderate disease and potentially serving as long-term maintenance therapy with a favorable safety profile.

Therapy 36
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Utility of Head-to-Head Studies in Psoriasis Management

Dermatology Times

Panelists discuss how head-to-head trials in psoriasis provide direct efficacy and safety comparisons between IL-17 inhibitors and other drug classes. Studies like BE RADIANT, BE VIVID, and IXORA-R highlight bimekizumabs and ixekizumabs superiority over secukinumab and ustekinumab. CLARITY and COBRA compare IL-17 to IL-23 inhibitors, while IMMerge and BE BOLD explore risankizumabs role.

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Gene Expression Profile Testing Offers Clinicians a Path to Safely Avoid SLNB in Low-Risk Melanoma Patients

Dermatology Times

New prospective data from the DECIDE study reinforce the role of the 31-GEP test in clinical decision-making.

Clinic 45
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Treatment Escalation and De-escalation Strategies in Pediatric AD: Positioning Ruxolitinib Cream in Clinical Decision-Making

Dermatology Times

James Song, MD, FAAD, discusses how clinicians should evaluate treatment response based on objective measures including BSA involvement, EASI scores, and pruritus ratings when determining whether to escalate from topical ruxolitinib to systemic therapy or de-escalate to maintenance treatment in pediatric atopic dermatitis patients.

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Future Directions for IL-17 Inhibitors in Psoriasis and Psoriatic Arthritis Care

Dermatology Times

Panelists discuss how medical professionals anticipate new IL-17 inhibitor data, particularly from head-to-head trials like BE BOLD. Interest is growing in sonelokimab, an IL-17A/F nanobody (Papp, 2021). Further research is needed on long-term efficacy, safety, and optimal patient selection.

Safety 36