Revealed: The Stress-Skin Allergy Connection
The Dermatology Digest
JANUARY 7, 2025
Stress impairs the ability of macrophages to clear dead cells from allergic lesions, worsening skin symptoms, new research suggests. More specifically, accumulated dead cells induce the expression of eosinophil-recruiting protein, CCL24, in the skin lesions. CCL24 production is dependent on the caspase-1 enzyme; thus, inhibiting caspase-1 can mitigate and even reverse allergy symptoms, the study authors report.
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