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The data presents compelling evidence for the sustained efficacy and safety of the oral JAK1 inhibitor in the treatment of moderate to severe atopic dermatitis over an extended 140-week period.
Jennifer Soung, MD, discusses how having more nonsteroidal options for long-term atopic dermatitis management is crucial, especially for younger children, to minimize potential side effects and support safer, sustained treatment.
Patricia Farris discusses skincare industry trends, including consumer demand for “clean beauty,” sustainability, and resources for consumer and dermatologist ingredient education. There’s plenty of natural things that can cause irritant contact dermatitis. We as dermatologists know that this isn’t true.
At Fall Clinical 2024, Christopher Bunick, MD, PhD, presented findings on the prevalence of systemic corticosteroid use among patients with atopic dermatitis and highlighted how those treated with upadacitinib achieved and sustained optimal skin clearance and itch relief long-term.
APG777 continues to show promise in atopic dermatitis (AD), according to early data. near-complete inhibition of pSTAT6 and sustained TARC inhibition out to nine months following a single dose These data will be presented at the American College of Allergy, Asthma & Immunology’s (ACAAI) 2024 Annual Scientific Meeting in Boston, MA.
Sanofi’s investigational OX40-ligand blocker amlitelimab produces sustained improvement in the signs and symptoms of atopic dermatitis (AD) in adults who previously responded and continued treatment and sustained off-drug improvements in those who stopped treatment.
Nemolizumab improves skin lesions, itch, and sleep disturbance in patients with moderate-to-severe atopic dermatitis (AD), according to results from two phase 3 studies. Galderma’s nemolizumab is a first-in-class interleukin-31 receptor alpha antagonist that is under investigation for atopic dermatitis.
Modulation of PKM2 alters B and T lymphocyte function and represents a novel therapeutic target with the potential to rebalance the immune system, normalize immune cell function and drive sustained disease remission in AD.
Pharmacokinetic (PK) data showed a half-life of approximately 75 days across doses tested and pharmacodynamic (PD) data showed, deep and sustained inhibition of key atopic dermatitis (AD) biomarkers pSTAT6 and TARC for ~3 months (longest follow-up available, with inhibition still ongoing at time of the data cut).
By investigating healthy skin, along with the skin of those with atopic dermatitis and other allergic skin disorders, the researchers may learn how to significantly slow the visible signs of aging in all people as well as in patients with eczema, who show signs of premature or accelerated aging.
Through this trial, we hope to continue to move the needle toward personalized therapies that can provide sustainable relief for coping with these debilitating conditions.” None of these medications, however, provide sustained relief. Gladwin, MD , who is the John Z. and Akiko K.
Now that you know the problem, we're here to guide you toward proactive, holistic, and sustainable strategies for not just managing the effects of stress on your skin but also improving your well-being. But we won't stop there. This can lead to redness and irritation, making your skin feel sensitive and uncomfortable.
Underlying Skin Conditions: Conditions like atopic dermatitis and rosacea can compromise the integrity of the skin barrier making it more prone to damage. [2] Effective strategies , such as immediate remedies for barrier damage, pH-balanced skincare, and sustainable skincare practices, can help you repair and protect your skin barrier. [4]
That means cleaning your hairbrush is a sustainability issue. Scientists believe that it is a proven effective treatment for atopic dermatitis. Scientists at The Ohio State University (go Buckeyes!) discovered that a lot of people just throw away their hairbrushes because they’re so hard to clean.
According to Fisher’s Contact Dermatitis, acne can result from topical application of cosmetic products via two mechanisms. The second is It MIGHT make sense from a sustainability point of view – you make the product more concentrated so you get more uses per bottle which reduces packaging waste.
It’s really hard to get our patients to use retinoids because they get retinoid dermatitis and they peel. Sustained improvement in photodamaged skin with reduced tretinoin emollient cream treatment regimen: effect of once-weekly and three-times-weekly applications. But even the lesser regimen is not so easy, said Dr. Baumann.
Some of the key highlights related to atopic dermatitis (AD) therapies include: APG777 APG777 is a novel, subcutaneous, extended half-life monoclonal antibody (mAb) targeting interleukin (IL)-13. Apogee Therapeutics recently hosted its first R&D Day, which featured updates across its entire portfolio.
Atopic dermatitis (AD) patients taking lebrikizumab (Ebglyss, Lilly) show a sustained depth of response for up to three years, according to new research presented at the2025American Academy of Dermatologys annual meeting in Orlando, FL.Raj Chovatiya, MD, PhD, Founder and Director of the Center for Medical Dermatology and Immunology Research in Chicago, (..)
Rezpegaldesleukin showed durable dose-dependent improvements in physician-assessed disease activity and patient-reported outcomes in patients with atopic dermatitis (AD) and psoriasis (PsO), according to two Phase 1b studies in Nature Communications. Chief Research & Development Officer at Nektar.
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