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Indeed, as reported in Nature, 9 a 2015 study found that while microbe-free mice failed to respond to treatment with checkpoint inhibitors, mice given Bacteroides fragilis fared much better. According to the authors, these differences could not be explained by renal function or poor diet.
According to Fisher’s Contact Dermatitis, acne can result from topical application of cosmeticproducts via two mechanisms. And you have to repeat that process for every product you want to evaluate. Even IF you did all that you still can’t really control for other factors like hormonal changes and changes in diet.
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